What is hepatitis C virus (HCV)?

What is hepatitis C virus (HCV)? Hepatitis C virus (HCV) was first definitively identified by molecular cloning of the virus genome in 1989, HCV was caused by Hepatitis C virus, and will risk health and life no less than HBV, the reasons are as follow: ① HCV disease is existing worldwide ② Easily develop into chronic hepatitis, and has close connection with hepatocirrhosis and liver cancer. HCV infection occurs in 78% - 94% infected liver transplant recipients. Since July 1st 1993 the Chinese government has screened all donated blood for HCV as well as HBV. HCV is blood-borne, which means that it is contracted only through blood-to-blood contact. BLOOD-TO-BLOOD contact includes: blood transfusions, tattoos, e.g.: drug use, passage of mother to unborn, or shared razors. In the majority of cases HCV infection gives rise to acute HCV, chronic HCV, hepatocirrhosis and liver cancer. There is also someone who is healthy but still HCV carrier. Almost all patients develop a vigorous antibody and cell-mediated immune response which fails to clear the infection but may contribute towards liver damage. Most flavivirus infections are cytopathic, but this has not been directly tested in the case of HCV since the virus cannot be cultured. HBV disease usually start without any obvious symptom, in some typical acute HCV case, HCV antibody will become positive after one month or more. If this positive last for four months then it becomes chronic HCV disease, at least 50% - 75% cases of HCV infection become chronic hepatitis and will become hepatocirrhosis or liver cancer at last.


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